Excessive Underarm Sweating

Excessive underarm sweating is more common than you think

Around 10 million people in the US are living with excessive underarm sweating

Excessive underarm sweating, also known as primary axillary hyperhidrosis, is a common condition. It occurs when the underarm sweat glands produce more sweat than the body needs, often causing it to soak through clothing.

It is an ongoing condition that commonly starts during your teen years and can continue into adulthood.

Worries about excessive sweating can seep into everyday life

If sweating is always on your mind—you’re not the only one. People with excessive underarm sweating can experience anxiety and embarrassment related to how much they sweat, making it harder to interact with others. This can impact work, school, and relationships.

In a survey, the majority of people with excessive underarm sweating said they constantly worried about whether their sweat was noticeable

Has hiding sweat stains become your signature style?

Like many people with excessive underarm sweating, you’ve probably had to get creative to hide visible underarm sweat stains, whether it’s by:

  • Frequently changing clothes
  • Wearing dark loose clothing
  • Layering (even when it’s not sweater weather)
  • Being hyper-aware of the fabrics you do choose to wear (Silk? No thanks!)
  • Putting napkins in your armpits under your clothes

Know that excessive underarm sweating can be treated

It is a common, diagnosable condition. But many people with excessive underarm sweating wait years to talk to a doctor about their symptoms.

1 in 2 people with excessive sweating have never discussed it with a healthcare provider.

Is your underarm sweat excessive?

Talk to a healthcare provider about your excessive underarm sweating.

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Indication

Sofdra (sofpironium) topical gel, 12.45% is a prescription anticholinergic medicine used on the skin to treat excessive underarm sweating (primary axillary hyperhidrosis) in adults and children 9 years of age and older.

IMPORTANT SAFETY INFORMATION

Sofdra is for use on the skin in the underarm area only. After applying Sofdra, wash your hands right away and do not touch your underarms. Sofdra is flammable. Avoid heat and flame while applying Sofdra.

Who should not use Sofdra?

Do not use Sofdra if you have certain medical conditions that can be made worse by taking an anticholinergic medicine, such as glaucoma, severe ulcerative colitis (UC) or other serious bowel problems, myasthenia gravis, and Sjogren’s syndrome.

What should I tell my healthcare provider before using Sofdra?

  • Tell your healthcare provider about all of your medical conditions, including prostate, bladder or kidney problems, problems passing urine, if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if Sofdra will harm your unborn baby or pass into your breast milk.
  • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, especially any anticholinergic medicines.

What are possible side effects of Sofdra?

Serious side effects may include:

  • Urinary retention. Stop using Sofdra and call your healthcare provider right away if you have difficulty urinating, urinate frequently or in a weak stream or drips, a full bladder or difficulty emptying your bladder.
  • Problems with control of your body temperature. Stop using Sofdra and call your healthcare provider right away if you have decreased sweating that develops into symptoms of heat illness (e.g., hot, red skin; passing out; fast, weak pulse; fast, shallow breathing; increased body temperature).
  • Blurred vision. Stop using Sofdra, call your healthcare provider right away, and do not drive or operate machinery or do hazardous work until your vision is clear.

The most common side effects of Sofdra include dry mouth; blurred vision; pain, redness, swelling, itching, and irritation in the underarm area; dilation of the pupils of your eyes; and problems with urination.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088. You may also report side effects to Botanix at 1‑866‑763‑6337.

Keep Sofdra and all medicines out of the reach of children.

Please see full Prescribing Information, Patient Product Information, and Instructions for Use.

This site is intended for US residents only.

Sofdra is a trademark of Botanix SB Inc.
© 2025 Botanix SB Inc. All rights reserved.
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